ERYTHEMA INFECTIOSUM FIFTH DISEASE PDF

Parvovirus B19 causes fifth disease. What are the symptoms of fifth disease? There may be no symptoms or only mild symptoms. It starts as a very red rash on the cheeks that looks like the face has been slapped.

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See more images of erythema infectiosum What are the symptoms of erythema infectiosum? Parvovirus B19 infection causes nonspecific viral symptoms such as mild fever and headache at first.

The rash, erythema infectiosum, appears a few days later with firm red cheeks, which feel burning hot. This lasts 2 to 4 days, and is followed by a pink rash on the limbs and sometimes the trunk. This develops a lace-like or network pattern. Although most prominent in the first few days, the rash can persist for up to six weeks at least intermittently, and is most obvious when warm.

Complications of erythema infectiosum Although usually a mild childhood condition, erythrovirus B19 infection can result in complications. This can occur if erythema infectiosum occurs in the first half of pregnancy. Parvovirus B19 does not cause congenital malformations.

As the risk of an adverse outcome is low, the infection is not routinely screened for in pregnancy Chronic parvovirus infection in immunodeficient patients, such as organ transplant recipients, causing erythropoietin-resistant anaemia, proteinuria, and glomerulosclerosis in a renal allograft Rarely, encephalitis, hepatitis, non-occlusive bowel infarction, amegakaryocytic thrombocytopenia, myositis and heart disease How is the diagnosis of erythema infectiosum made?

In most cases, erythema infectiosum is a clinical diagnosis in a child with characteristic slapped cheek and lacy rash. Parvovirus can cause other rashes such as a papular purpuric gloves and socks syndrome. The diagnosis can be confirmed by blood tests. Parvovirus serology: IgG, IgM. This test is reported in about 7 days.

Parvovirus PCR is more sensitive. This test is reported in about 3 days. In situ hybridisation or immunohistochemistry on biopsy specimens If the child is unwell, or has haemolytic anaemia, a full blood count should be performed.

Ultrasound examination and Doppler examination of at-risk pregancies can detect hydrops fetalis. Treatment of erythema infectiosum Erythema infectiosum is not generally a serious condition. There is no specific treatment. Affected children may remain at school, as the infectious stage or viraemia occurs before the rash is evident.

The application of an ice-cold flannel can relieve the discomfort of burning hot cheeks. Red blood cell transfusions and immunoglobulin therapy can be successful in chronic parvovirus infection or during an aplastic crisis. Hydrops fetalis due to parvovirus infection is treated by intrauterine transfusion.

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Erythema infectiosum

Parents, or people working with children, are also liable to infection. The most striking symptom is a red rash on the cheeks. There is no cure — in time the infection goes. How is erythema infectiosum contracted? Erythema infectiosum is caused by a virus called parvovirus B

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Fifth disease (Erythema Infectiosum)

See more images of erythema infectiosum What are the symptoms of erythema infectiosum? Parvovirus B19 infection causes nonspecific viral symptoms such as mild fever and headache at first. The rash, erythema infectiosum, appears a few days later with firm red cheeks, which feel burning hot. This lasts 2 to 4 days, and is followed by a pink rash on the limbs and sometimes the trunk. This develops a lace-like or network pattern. Although most prominent in the first few days, the rash can persist for up to six weeks at least intermittently, and is most obvious when warm.

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